Submitting Modification, Renewal or Closure

Protocols should only be closed if they are no longer interacting with subjects and all data has been collected, the data has been “cleaned,” analysis of identifiable data is complete, and all identifiers have been removed from data sets. When a study ends, is closed, canceled for any reason, or is prematurely completed you must complete a Closure form. A Closure form serves as notification to the IRB that study activity is no longer being performed. 

DO NOT CLOSE THE PROJECT TOO SOON! Once a Closure Form is processed, no further research-related activity can occur and any contact with subjects or access to data for research purposes will no longer be allowed. 

The Principal Investigator is responsible for submitting a closure report, indicating any research findings and/or outcome of the project. All protocols are approved for the time period as stated in the IRB approval letters. Prior to the end of the last year of the protocol, the investigators are required to submit a closure report. 

Below is a guide to explain how to submit a Closure request for your approved study.

1. Click https://queens.app.cayuse.com to log in
2. Navigate to the Human Ethics portal
3. In the upper right-hand corner, click blue button +”Closure”
4. Select Edit.
5. Complete the Closure page.
6. Once complete, mark the routing button as “Complete Submission”
7. The Principal Investigator will receive a notice to “Certify” the submission.
8. Once the principal investigator certifies, the submission will be received by the RRO and will undergo review.

For visual instructions, please visit https://support.cayuse.com/hc/en-us/articles/360052709533-Closing-a-Study-in-Human-Ethics