OFFICE OF RESEARCH AND DEVELOPMENT (ORD)

Office of Research and Development

Office of Research and Development
The Queen’s Medical Center
1301 Punchbowl Street, UHT 508
Honolulu, HI 96813

Getting Started

Initial Submission

Below is a step-by-step summary of how to create, complete, and submit and new study: 

  1. Click https://queens.app.cayuse.com to log in.
  2. In the upper right-hand corner, click blue button “+ New Study”
  3. Complete the title of your study and click save.
  4. In the upper right-hand corner, click the blue button “+ New Submission”.
  5. You will now see a ribbon that says “Unsubmitted”. You will have the choice to edit, delete, or pdf the submission.
  6. Select Edit.
  7. If you are not the principal investigator of the study, first add yourself as the primary contact in the personnel section, and then edit the personnel to list the appropriate principal investigator.
  8. Continue with the other sections until complete.
  9. The principal investigator will receive an email notice to certify the submission.
  10. Once the principal investigator certifies, the submission will be received by the Research Regulatory Office and will undergo review.

For help submitting a new study (new submission) to the QMC RIRC, consult this Investigator’s Guide (TBD).

If you still have questions, contact RIRC@queens.org to schedule a meeting with RRO Staff who can assist with your submission. 

For additional assistance, you can visit the following site for visual instructions: https://support.cayuse.com/hc/en-us/articles/15128050897683-How-do-I-create-an-initial-submission 

Quick Links

IRB Review and Approval

All IRB submissions are reviewed in the order that they are received. You can check on the status of your protocol in the Cayuse Human Ethics System from your Cayuse Dashboard. 

Once the Regulatory Analyst has conducted an initial review of your study, if clarification or revisions are needed, we will return the study to you in the Cayuse Human Ethics System for edits. You will receive an email from the Cayuse Human Ethics System, which will let you know your protocol has been returned. Please complete the revisions in their entirety ASAP and resubmit the revised documents within the Cayuse Human Ethics System, following the steps above.

For instructions on how to address IRB review questions or concerns that have been returned to the researcher, please the Frequently Asked Questions page 

Once you receive an official approval letter from the IRB via the Cayuse Human Ethics System, you are welcome to begin your research activities. Note that you cannot begin research activities (including recruiting human subjects or collecting human subject data) until the IRB has officially issued you an approval letter for your IRB protocol. 

You may find your approved informed consent document on the study details page of your IRB submission. It will be located on the attachments tab at the bottom of the page. 

All approvals are final, and nothing may be changed once approval is issued without obtaining IRB approval for the changes. After your protocol is approved, a modification request must be reviewed and approved by the IRB before changes may be implemented. Failure to obtain IRB approval prior to the implementation of changes is considered noncompliance and will be subject to corrective action. This includes, but is not limited to, changes to study documents, personnel, activities, recruitment methods, or to your Cayuse submission form. 

For instructions on how to access or download IRB determination letters for your study, please visit the Frequently Asked Questions page. 

If you have any questions, please contact:

rirc@queens.org